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Detailed evaluation of the upper airway in the Dp(16)1Yey mouse model of Down syndrome
A high prevalence of obstructive sleep apnea (OSA) has been reported in Down syndrome (DS) owing to the coexistence of multiple predisposing factors related to its genetic abnormality, posing a challenge for the management of OSA. We hypothesized that DS mice recapitulate craniofacial abnormalities...
Autores principales: | Takahashi, Tatsunori, Sakai, Noriaki, Iwasaki, Tomonori, Doyle, Timothy C., Mobley, William C., Nishino, Seiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721723/ https://www.ncbi.nlm.nih.gov/pubmed/33288820 http://dx.doi.org/10.1038/s41598-020-78278-2 |
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