Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression

Recent data suggest that Pancreatic Neuroendocrine Tumours (PanNETs) originate from α- or β-cells of the islets of Langerhans. The majority of PanNETs are non-functional and do not express cell-type specific hormones. In the current study we examine whether tumour DNA methylation (DNAme) profiling c...

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Detalles Bibliográficos
Autores principales: Di Domenico, Annunziata, Pipinikas, Christodoulos P., Maire, Renaud S., Bräutigam, Konstantin, Simillion, Cedric, Dettmer, Matthias S., Vassella, Erik, Thirlwell, Chrissie, Perren, Aurel, Marinoni, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721725/
https://www.ncbi.nlm.nih.gov/pubmed/33288854
http://dx.doi.org/10.1038/s42003-020-01479-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721725/
https://www.ncbi.nlm.nih.gov/pubmed/33288854
http://dx.doi.org/10.1038/s42003-020-01479-y

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