Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia

The bioactive vitamin D(3), 1α,25(OH)(2)D(3), plays a central role in calcium homeostasis by controlling the activity of the vitamin D receptor (VDR) in various tissues. Hypercalcemia secondary to high circulating levels of vitamin D(3) leads to hypercalciuria, nephrocalcinosis and renal dysfunction...

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Detalles Bibliográficos
Autores principales: Rovito, Daniela, Belorusova, Anna Y., Chalhoub, Sandra, Rerra, Anna-Isavella, Guiot, Elvire, Molin, Arnaud, Linglart, Agnès, Rochel, Natacha, Laverny, Gilles, Metzger, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721737/
https://www.ncbi.nlm.nih.gov/pubmed/33288743
http://dx.doi.org/10.1038/s41467-020-20069-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721737/
https://www.ncbi.nlm.nih.gov/pubmed/33288743
http://dx.doi.org/10.1038/s41467-020-20069-4

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