Impact of hypoxia on the double-strand break repair after photon and carbon ion irradiation of radioresistant HNSCC cells

DNA double-strand breaks (DSBs) induced by photon irradiation are the most deleterious damage for cancer cells and their efficient repair may contribute to radioresistance, particularly in hypoxic conditions. Carbon ions (C-ions) act independently of the oxygen concentration and trigger complex- and...

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Detalles Bibliográficos
Autores principales: Wozny, Anne-Sophie, Alphonse, Gersende, Cassard, Audrey, Malésys, Céline, Louati, Safa, Beuve, Michael, Lalle, Philippe, Ardail, Dominique, Nakajima, Tetsuo, Rodriguez-Lafrasse, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721800/
https://www.ncbi.nlm.nih.gov/pubmed/33288855
http://dx.doi.org/10.1038/s41598-020-78354-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721800/
https://www.ncbi.nlm.nih.gov/pubmed/33288855
http://dx.doi.org/10.1038/s41598-020-78354-7

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