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Baculovirus-free insect cell expression system for high yield antibody and antigen production

Antibodies are essential tools for therapy and diagnostics. Yet, production remains expensive as it is mostly done in mammalian expression systems. As most therapeutic IgG require mammalian glycosylation to interact with the human immune system, other expression systems are rarely used for productio...

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Detalles Bibliográficos
Autores principales: Korn, Janin, Schäckermann, Dorina, Kirmann, Toni, Bertoglio, Federico, Steinke, Stephan, Heisig, Janyn, Ruschig, Maximilian, Rojas, Gertrudis, Langreder, Nora, Wenzel, Esther Veronika, Roth, Kristian Daniel Ralph, Becker, Marlies, Meier, Doris, van den Heuvel, Joop, Hust, Michael, Dübel, Stefan, Schubert, Maren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721901/
https://www.ncbi.nlm.nih.gov/pubmed/33288836
http://dx.doi.org/10.1038/s41598-020-78425-9