Preclinical comparison of four [(18)F, (nat)Ga]rhPSMA-7 isomers: influence of the stereoconfiguration on pharmacokinetics

INTRODUCTION: Radiohybrid (rh) ligands, a novel class of prostate-specific membrane antigen (PSMA)-targeted radiopharmaceuticals, can be labeled either with [(18)F]fluorine via isotopic exchange or with radiometals (such as [(68)Ga]Gallium, [(177)Lu]Lutetium, [(225)Ac]Actinium). Among these, [(18)F,...

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Detalles Bibliográficos
Autores principales: Wurzer, Alexander, Parzinger, Mara, Konrad, Matthias, Beck, Roswitha, Günther, Thomas, Felber, Veronika, Färber, Stefanie, Di Carlo, Daniel, Wester, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721954/
https://www.ncbi.nlm.nih.gov/pubmed/33284394
http://dx.doi.org/10.1186/s13550-020-00740-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721954/
https://www.ncbi.nlm.nih.gov/pubmed/33284394
http://dx.doi.org/10.1186/s13550-020-00740-z

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