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Urine and serum S100A8/A9 and S100A12 associate with active lupus nephritis and may predict response to rituximab treatment

BACKGROUND: Approximately 30% of patients with the systemic autoimmune/inflammatory disorder systemic lupus erythematosus (SLE) develop lupus nephritis (LN) that affects treatment and prognosis. Easily accessible biomarkers do not exist to reliably predict renal disease. The Maximizing SLE Therapeut...

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Detalles Bibliográficos
Autores principales: Davies, Jennifer C, Midgley, Angela, Carlsson, Emil, Donohue, Sean, Bruce, Ian N, Beresford, Michael W, Hedrich, Christian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722276/
https://www.ncbi.nlm.nih.gov/pubmed/32723832
http://dx.doi.org/10.1136/rmdopen-2020-001257