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Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing
BACKGROUND: The presence of nuclear mitochondrial DNA (numtDNA) has been reported within several nuclear genomes. Next to mitochondrial protein-coding genes, numtDNA sequences also encode for mitochondrial tRNA genes. However, the biological roles of numtDNA remain elusive. RESULTS: Employing in sil...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722341/ https://www.ncbi.nlm.nih.gov/pubmed/33292386 http://dx.doi.org/10.1186/s13059-020-02199-6 |