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Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing
BACKGROUND: The presence of nuclear mitochondrial DNA (numtDNA) has been reported within several nuclear genomes. Next to mitochondrial protein-coding genes, numtDNA sequences also encode for mitochondrial tRNA genes. However, the biological roles of numtDNA remain elusive. RESULTS: Employing in sil...
Autores principales: | Hoser, Simon M., Hoffmann, Anne, Meindl, Andreas, Gamper, Maximilian, Fallmann, Jörg, Bernhart, Stephan H., Müller, Lisa, Ploner, Melanie, Misslinger, Matthias, Kremser, Leopold, Lindner, Herbert, Geley, Stephan, Schaal, Heiner, Stadler, Peter F., Huettenhofer, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722341/ https://www.ncbi.nlm.nih.gov/pubmed/33292386 http://dx.doi.org/10.1186/s13059-020-02199-6 |
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