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Nrf2-activating Therapy Accelerates Wound Healing in a Model of Cutaneous Chronic Venous Insufficiency

BACKGROUND: Chronic venous insufficiency (CVI) stems from venous hypertension, extravasation of blood, and iron-rich skin deposits. The latter is central to ulcer development through generating reactive oxygen species (ROS) that drive persistent local inflammation and the development of lipodermatos...

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Detalles Bibliográficos
Autores principales: Kuhn, Joseph, Sultan, Darren L., Waqas, Bukhtawar, Ellison, Trevor, Kwong, Jennifer, Kim, Camille, Hassan, Absara, Rabbani, Piul S., Ceradini, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722614/
https://www.ncbi.nlm.nih.gov/pubmed/33299679
http://dx.doi.org/10.1097/GOX.0000000000003006