Combination of the phosphodiesterase 10A inhibitor, MR1916 with risperidone shows additive antipsychotic‐like effects without affecting cognitive enhancement and cataleptic effects in rats

AIM: Phosphodiesterase 10A (PDE10A) inhibitors not only have antipsychotic‐like effects but also cause cognitive enhancement without affecting extrapyramidal side effects in rodents, suggesting that PDE10A may be a novel approach for the treatment of schizophrenia. However, how a combination of PDE1...

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Detalles Bibliográficos
Autores principales: Arakawa, Keita, Maehara, Shunsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722671/
https://www.ncbi.nlm.nih.gov/pubmed/32351052
http://dx.doi.org/10.1002/npr2.12108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722671/
https://www.ncbi.nlm.nih.gov/pubmed/32351052
http://dx.doi.org/10.1002/npr2.12108

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