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Forskolin rapidly enhances neuron‐like morphological change of directly induced‐neuronal cells from neurofibromatosis type 1 patients

AIM: Neurofibromatosis type 1 (NF1) is a multifaceted disease, and frequently comorbid with neurodevelopmental disorders such as autism spectrum disorder (ASD) and learning disorder. Dysfunction of adenylyl cyclase (AC) is one of the candidate pathways in abnormal development of neuronal cells in th...

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Detalles Bibliográficos
Autores principales: Sagata, Noriaki, Kano, Shin‐ichi, Ohgidani, Masahiro, Inamine, Shogo, Sakai, Yasunari, Kato, Hiroki, Masuda, Keiji, Nakahara, Takeshi, Nakahara‐Kido, Makiko, Ohga, Shouichi, Furue, Masutaka, Sawa, Akira, Kanba, Shigenobu, Kato, Takahiro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722681/
https://www.ncbi.nlm.nih.gov/pubmed/33037790
http://dx.doi.org/10.1002/npr2.12144