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Increased apolipoprotein E and decreased TNF‐α in the cerebrospinal fluid of nondemented APOE‐ε4 carriers

AIM: The ε4 allele of apolipoprotein E gene (APOE) is a well‐known risk factor of late‐onset Alzheimer's disease. However, little is known why this variant confers a risk for Alzheimer's disease. The aim of this study was to examine the influence of the APOE genotype on cerebrospinal fluid...

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Detalles Bibliográficos
Autores principales: Sasayama, Daimei, Hattori, Kotaro, Yokota, Yuuki, Matsumura, Ryo, Teraishi, Toshiya, Yoshida, Sumiko, Kunugi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722685/
https://www.ncbi.nlm.nih.gov/pubmed/32426945
http://dx.doi.org/10.1002/npr2.12110