Efficient viral delivery of Cas9 into human safe harbor

Gene editing using CRISPR/Cas9 is a promising method to cure many human genetic diseases. We have developed an efficient system to deliver Cas9 into the adeno-associated virus integration site 1 (AAVS1) locus, known as a safe harbor, using lentivirus and AAV viral vectors, as a step toward future in...

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Detalles Bibliográficos
Autores principales: Hayashi, Hideki, Kubo, Yoshinao, Izumida, Mai, Matsuyama, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722726/
https://www.ncbi.nlm.nih.gov/pubmed/33293588
http://dx.doi.org/10.1038/s41598-020-78450-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722726/
https://www.ncbi.nlm.nih.gov/pubmed/33293588
http://dx.doi.org/10.1038/s41598-020-78450-8

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