Cargando…

Sis1 potentiates the stress response to protein aggregation and elevated temperature

Cells adapt to conditions that compromise protein conformational stability by activating various stress response pathways, but the mechanisms used in sensing misfolded proteins remain unclear. Moreover, aggregates of disease proteins often fail to induce a productive stress response. Here, using a y...

Descripción completa

Detalles Bibliográficos
Autores principales: Klaips, Courtney L., Gropp, Michael H. M., Hipp, Mark S., Hartl, F. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722728/
https://www.ncbi.nlm.nih.gov/pubmed/33293525
http://dx.doi.org/10.1038/s41467-020-20000-x