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FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner

Pathological angiogenesis is an important component of hepatic fibrosis along with fibrous deposition, but its role is not well understood. Here, we demonstrated that fibronectin containing extra domain A(FN-EDA), a fibronectin splice variant highly expressed in hepatic fibrosis, mediated angiogenes...

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Detalles Bibliográficos
Autores principales: Su, Xiaonan, Ma, Xiaowen, Xie, Xiaoyu, Wu, Hao, Wang, Le, Feng, Yuemin, Yu, Zhen, Liu, Chenxi, Qi, Jianni, Zhu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722740/
https://www.ncbi.nlm.nih.gov/pubmed/33293521
http://dx.doi.org/10.1038/s41420-020-00378-9