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FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner
Pathological angiogenesis is an important component of hepatic fibrosis along with fibrous deposition, but its role is not well understood. Here, we demonstrated that fibronectin containing extra domain A(FN-EDA), a fibronectin splice variant highly expressed in hepatic fibrosis, mediated angiogenes...
Autores principales: | Su, Xiaonan, Ma, Xiaowen, Xie, Xiaoyu, Wu, Hao, Wang, Le, Feng, Yuemin, Yu, Zhen, Liu, Chenxi, Qi, Jianni, Zhu, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722740/ https://www.ncbi.nlm.nih.gov/pubmed/33293521 http://dx.doi.org/10.1038/s41420-020-00378-9 |
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