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Deep sequencing detects human papillomavirus (HPV) in cervical cancers negative for HPV by PCR

BACKGROUND: Human papillomavirus (HPV) is a necessary cause of cervical cancer, although some invasive cervical cancers may test negative by HPV PCR. We previously requested all invasive cervical cancers in Sweden during 10 years and subjected them to PCR. We also optimised methods for deep sequenci...

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Detalles Bibliográficos
Autores principales: Arroyo Mühr, Laila Sara, Lagheden, Camilla, Lei, Jiayao, Eklund, Carina, Nordqvist Kleppe, Sara, Sparén, Pär, Sundström, Karin, Dillner, Joakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722749/
https://www.ncbi.nlm.nih.gov/pubmed/33020595
http://dx.doi.org/10.1038/s41416-020-01111-0