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Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

Alzheimer’s disease (AD) is characterized by the appearance of amyloid‐β plaques, neurofibrillary tangles, and inflammation in brain regions involved in memory. Using mass spectrometry, we have quantified the phosphoproteome of the CK‐p25, 5XFAD, and Tau P301S mouse models of neurodegeneration. We i...

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Detalles Bibliográficos
Autores principales: Morshed, Nader, Ralvenius, William T, Nott, Alexi, Watson, L Ashley, Rodriguez, Felicia H, Akay, Leyla A, Joughin, Brian A, Pao, Ping‐Chieh, Penney, Jay, LaRocque, Lauren, Mastroeni, Diego, Tsai, Li‐Huei, White, Forest M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722784/
https://www.ncbi.nlm.nih.gov/pubmed/33289969
http://dx.doi.org/10.15252/msb.20209819