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An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydomonas

Silencing of exogenous DNA can make transgene expression very inefficient. Genetic screens in the model alga Chlamydomonas have demonstrated that transgene silencing can be overcome by mutations in unknown gene(s), thus producing algal strains that stably express foreign genes to high levels. Here,...

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Detalles Bibliográficos
Autores principales: Neupert, Juliane, Gallaher, Sean D., Lu, Yinghong, Strenkert, Daniela, Segal, Na’ama, Barahimipour, Rouhollah, Fitz-Gibbon, Sorel T., Schroda, Michael, Merchant, Sabeeha S., Bock, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722844/
https://www.ncbi.nlm.nih.gov/pubmed/33293544
http://dx.doi.org/10.1038/s41467-020-19983-4