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Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrophage activation to improve disease outcome. Here,...

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Detalles Bibliográficos
Autores principales: Baardman, Jeroen, Verberk, Sanne G. S., van der Velden, Saskia, Gijbels, Marion J. J., van Roomen, Cindy P. P. A., Sluimer, Judith C., Broos, Jelle Y., Griffith, Guillermo R., Prange, Koen H. M., van Weeghel, Michel, Lakbir, Soufyan, Molenaar, Douwe, Meinster, Elisa, Neele, Annette E., Kooij, Gijs, de Vries, Helga E., Lutgens, Esther, Wellen, Kathryn E., de Winther, Menno P. J., Van den Bossche, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722882/
https://www.ncbi.nlm.nih.gov/pubmed/33293558
http://dx.doi.org/10.1038/s41467-020-20141-z