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Prognostic and predictive significance of nuclear HIF1α expression in locally advanced HNSCC patients treated with chemoradiation with or without nimotuzumab

BACKGROUND: Anti-EGFR-based therapies have limited success in HNSCC patients. Predictive biomarkers are greatly needed to identify the patients likely to be benefited from these targeted therapies. Here, we present the prognostic and predictive association of biomarkers in HPV-negative locally advan...

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Detalles Bibliográficos
Autores principales: Patel, Usha, Pandey, Manish, Kannan, Sadhana, Samant, Tanuja A., Gera, Poonam, Mittal, Neha, Rane, Swapnil, Patil, Asawari, Noronha, Vanita, Joshi, Amit, Patil, Vijay M., Prabhash, Kumar, Mahimkar, Manoj B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722894/
https://www.ncbi.nlm.nih.gov/pubmed/32939054
http://dx.doi.org/10.1038/s41416-020-01064-4