Loss of miR-100 and miR-125b results in cancer stem cell properties through IGF2 upregulation in hepatocellular carcinoma

Stemness factors control microRNA expression in cancer stem cells. Downregulation of miR-100 and miR-125b is associated with tumor progression and prognosis of various cancers. Comparing miRNA profiling of patient-derived tumorsphere (TS) and adherent (2D) hepatocellular carcinoma cells, miR-100 and...

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Detalles Bibliográficos
Autores principales: Seol, Hyang Sook, Akiyama, Yoshimitsu, Lee, San-Eun, Shimada, Shu, Jang, Se Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722933/
https://www.ncbi.nlm.nih.gov/pubmed/33293585
http://dx.doi.org/10.1038/s41598-020-77960-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722933/
https://www.ncbi.nlm.nih.gov/pubmed/33293585
http://dx.doi.org/10.1038/s41598-020-77960-9

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