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Loss of miR-100 and miR-125b results in cancer stem cell properties through IGF2 upregulation in hepatocellular carcinoma
Stemness factors control microRNA expression in cancer stem cells. Downregulation of miR-100 and miR-125b is associated with tumor progression and prognosis of various cancers. Comparing miRNA profiling of patient-derived tumorsphere (TS) and adherent (2D) hepatocellular carcinoma cells, miR-100 and...
Autores principales: | Seol, Hyang Sook, Akiyama, Yoshimitsu, Lee, San-Eun, Shimada, Shu, Jang, Se Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722933/ https://www.ncbi.nlm.nih.gov/pubmed/33293585 http://dx.doi.org/10.1038/s41598-020-77960-9 |
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