CB11, a novel purine-based PPARɣ ligand, overcomes radio-resistance by regulating ATM signalling and EMT in human non-small-cell lung cancer cells

BACKGROUND: Peroxisome proliferator-activated receptor γ (PPARγ) agonists frequently induce cell death in human non-small-cell lung cancer (NSCLC) cells. However, majority of NSCLC patients acquire resistance after cancer therapy, and it is still unclear. METHODS: In this study we investigated the a...

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Detalles Bibliográficos
Autores principales: Kim, Tae Woo, Hong, Da-Won, Park, Joung Whan, Hong, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723055/
https://www.ncbi.nlm.nih.gov/pubmed/32958825
http://dx.doi.org/10.1038/s41416-020-01088-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723055/
https://www.ncbi.nlm.nih.gov/pubmed/32958825
http://dx.doi.org/10.1038/s41416-020-01088-w

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