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The mRNA expression of Il6 and Pdcd1 are predictive and protective factors for doxorubicin-induced cardiotoxicity

Anthracyclines, such as doxorubicin (DOX), have been widely used in the treatment of a number of different solid and hematological malignancies. However, these drugs can inflict cumulative dose-dependent and irreversible damage to the heart, and can occasionally lead to heart failure. The cardiotoxi...

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Detalles Bibliográficos
Autores principales: Kanno, Syu-Ichi, Hara, Akiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723161/
https://www.ncbi.nlm.nih.gov/pubmed/33300057
http://dx.doi.org/10.3892/mmr.2020.11752