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Optimal control to reach eco-evolutionary stability in metastatic castrate-resistant prostate cancer

In the absence of curative therapies, treatment of metastatic castrate-resistant prostate cancer (mCRPC) using currently available drugs can be improved by integrating evolutionary principles that govern proliferation of resistant subpopulations into current treatment protocols. Here we develop what...

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Detalles Bibliográficos
Autores principales: Cunningham, Jessica, Thuijsman, Frank, Peeters, Ralf, Viossat, Yannick, Brown, Joel, Gatenby, Robert, Staňková, Kateřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723267/
https://www.ncbi.nlm.nih.gov/pubmed/33290430
http://dx.doi.org/10.1371/journal.pone.0243386