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Optimal control to reach eco-evolutionary stability in metastatic castrate-resistant prostate cancer
In the absence of curative therapies, treatment of metastatic castrate-resistant prostate cancer (mCRPC) using currently available drugs can be improved by integrating evolutionary principles that govern proliferation of resistant subpopulations into current treatment protocols. Here we develop what...
Autores principales: | Cunningham, Jessica, Thuijsman, Frank, Peeters, Ralf, Viossat, Yannick, Brown, Joel, Gatenby, Robert, Staňková, Kateřina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723267/ https://www.ncbi.nlm.nih.gov/pubmed/33290430 http://dx.doi.org/10.1371/journal.pone.0243386 |
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