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BRD2 regulation of sigma-2 receptor upon cholesterol deprivation

The sigma-2 receptor (S2R) has long been pharmacologically targeted for antipsychotic treatment and tumor imaging. Only recently was it known for its coding gene and for its role implicated in cholesterol homeostasis. Here, we have investigated the transcriptional control of S2R by the Bromo/ExtraTe...

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Detalles Bibliográficos
Autores principales: Shen, Hongtao, Li, Jing, Xie, Xiujie, Yang, Huan, Zhang, Mengxue, Wang, Bowen, Kent, K Craig, Plutzky, Jorge, Guo, Lian-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723276/
https://www.ncbi.nlm.nih.gov/pubmed/33234676
http://dx.doi.org/10.26508/lsa.201900540