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A new pharmacodynamic approach to study antibiotic combinations against enterococci in vivo: Application to ampicillin plus ceftriaxone

The combination of ampicillin (AMP) and ceftriaxone (CRO) is considered synergistic against Enterococcus faecalis based on in vitro tests and the rabbit endocarditis model, however, in vitro assays are limited by the use of fixed antibiotic concentrations and the rabbit model by poor bacterial growt...

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Detalles Bibliográficos
Autores principales: Jimenez-Toro, Ivone, Rodriguez, Carlos A., Zuluaga, Andres F., Otalvaro, Julian D., Vesga, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723291/
https://www.ncbi.nlm.nih.gov/pubmed/33290425
http://dx.doi.org/10.1371/journal.pone.0243365