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HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes

Combination antiretroviral therapy (cART) has transformed HIV-1 infection, once a fatal illness, into a manageable chronic condition. Drug resistance, severe side effects and treatment noncompliance bring challenges to the cART implementation in clinical settings and indicate the need for additional...

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Detalles Bibliográficos
Autores principales: Xiao, Tianshu, Frey, Gary, Fu, Qingshan, Lavine, Christy L., Scott, David A., Seaman, Michael S., Chou, James J., Chen, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723321/
https://www.ncbi.nlm.nih.gov/pubmed/32152540
http://dx.doi.org/10.1038/s41589-020-0496-y