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Dynamic visualization of type II peptidyl carrier protein recognition in pyoluteorin biosynthesis

Using a covalent chemical probe and X-ray crystallography coupled to nuclear magnetic resonance data, we elucidated the dynamic molecular basis of protein recognition between the carrier protein and adenylation domain in pyoluteorin biosynthesis. These findings reveal a unique binding mode, which co...

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Detalles Bibliográficos
Autores principales: Corpuz, Joshua C., Podust, Larissa M., Davis, Tony D., Jaremko, Matt J., Burkart, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723355/
https://www.ncbi.nlm.nih.gov/pubmed/33305272
http://dx.doi.org/10.1039/c9cb00015a