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Zinc and SARS-CoV-2: A molecular modeling study of Zn interactions with RNA-dependent RNA-polymerase and 3C-like proteinase enzymes
RNA-dependent RNA-polymerase (RdRp) and 3C-like proteinase (3CL(pro)) are two main enzymes that play a key role in the replication of SARS-CoV-2. Zinc (Zn) has strong immunogenic properties and is known to bind to a number of proteins, modulating their activities. Zn also has a history of use in vir...
Autores principales: | Pormohammad, Ali, Monych, Nadia K., Turner, Raymond J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723401/ https://www.ncbi.nlm.nih.gov/pubmed/33236142 http://dx.doi.org/10.3892/ijmm.2020.4790 |
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