Icariin Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension via the Inhibition of TGF-β1/Smads Pathway in Rats

BACKGROUND: Pulmonary artery remodeling is important in the development of pulmonary artery hypertension. The TGF-β1/Smads signaling pathway is activated in pulmonary arterial hypertension (PAH) in rats. Icariin (ICA) suppresses the TGF-β1/Smad2 pathway in myocardial fibrosis in rats. Therefore, we...

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Detalles Bibliográficos
Autores principales: Xiang, Yijia, Cai, Changhong, Wu, Yonghui, Yang, Lebing, Ye, Shiyong, Zhao, Huan, Zeng, Chunlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723481/
https://www.ncbi.nlm.nih.gov/pubmed/33335559
http://dx.doi.org/10.1155/2020/9238428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723481/
https://www.ncbi.nlm.nih.gov/pubmed/33335559
http://dx.doi.org/10.1155/2020/9238428

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