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Autophagy-related gene 7 deficiency caused by miR-154-5p overexpression suppresses the cell viability and tumorigenesis of retinoblastoma by increasing cell apoptosis

BACKGROUND: Retinoblastoma is a rare cancer of the retina that accounts for 3% of all childhood cancers. The aim of this study was to illuminate the oncogenic role and potential molecular mechanisms of the microRNA miR-154-5p and autophagy-related gene 7 (ATG7) in retinoblastoma, and to establish a...

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Detalles Bibliográficos
Autores principales: Liu, Zhenrong, Huang, Yan, Zhang, Fan, Tang, Huairong, Wang, Youjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723560/
https://www.ncbi.nlm.nih.gov/pubmed/33313196
http://dx.doi.org/10.21037/atm-20-6009