Cargando…
Autophagy-related gene 7 deficiency caused by miR-154-5p overexpression suppresses the cell viability and tumorigenesis of retinoblastoma by increasing cell apoptosis
BACKGROUND: Retinoblastoma is a rare cancer of the retina that accounts for 3% of all childhood cancers. The aim of this study was to illuminate the oncogenic role and potential molecular mechanisms of the microRNA miR-154-5p and autophagy-related gene 7 (ATG7) in retinoblastoma, and to establish a...
Autores principales: | Liu, Zhenrong, Huang, Yan, Zhang, Fan, Tang, Huairong, Wang, Youjuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723560/ https://www.ncbi.nlm.nih.gov/pubmed/33313196 http://dx.doi.org/10.21037/atm-20-6009 |
Ejemplares similares
-
The retinoblastoma protein: multitasking to suppress tumorigenesis
por: Vormer, Tinke L., et al.
Publicado: (2015) -
Suppression of nicotinamide phosphoribosyltransferase expression by miR-154 reduces the viability of breast cancer cells and increases their susceptibility to doxorubicin
por: Bolandghamat Pour, Zahra, et al.
Publicado: (2019) -
Genistein suppresses retinoblastoma cell viability and growth and induces apoptosis by upregulating miR-145 and inhibiting its target ABCE1
por: Wei, Dong, et al.
Publicado: (2017) -
Intestinal epithelial cell autophagy deficiency suppresses inflammation-associated colon tumorigenesis
por: Liu, Hao, et al.
Publicado: (2022) -
Circ-ATAD1 is overexpressed in osteosarcoma (OS) and suppresses the maturation of miR-154-5p to increase cell invasion and migration
por: Zhou, Jihui, et al.
Publicado: (2021)