Platelet-rich plasma improves chronic inflammatory pain by inhibiting PKM2-mediated aerobic glycolysis in astrocytes

BACKGROUND: Astrocytes are highly glycolytic cells that play a crucial role in chronic pain. Recently it has been found that inflammation and metabolism are related to the inflammatory stimuli closely that cause cellular metabolic changes. Pyruvate kinase M2 (PKM2) is a critical metabolic kinase in...

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Detalles Bibliográficos
Autores principales: Wei, Xiang, Jin, Xiao-Hong, Meng, Xiao-Wen, Hua, Jie, Ji, Fu-Hai, Wang, Li-Na, Yang, Jian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723564/
https://www.ncbi.nlm.nih.gov/pubmed/33313201
http://dx.doi.org/10.21037/atm-20-6502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723564/
https://www.ncbi.nlm.nih.gov/pubmed/33313201
http://dx.doi.org/10.21037/atm-20-6502

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