Stromal cells promote chemoresistance of acute myeloid leukemia cells via activation of the IL-6/STAT3/OXPHOS axis

BACKGROUND: Bone marrow stromal cells (BMSCs) are known to promote chemoresistance in acute myeloid leukemia (AML) cells. However, the molecular basis for BMSC-associated AML chemoresistance remains largely unexplored. METHODS: The mitochondrial oxidative phosphorylation (OXPHOS) levels of AML cells...

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Detalles Bibliográficos
Autores principales: Hou, Diyu, Wang, Bin, You, Ruolan, Wang, Xiaoting, Liu, Jingru, Zhan, Weiwu, Chen, Ping, Qin, Tiandi, Zhang, Xuehao, Huang, Huifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723653/
https://www.ncbi.nlm.nih.gov/pubmed/33313091
http://dx.doi.org/10.21037/atm-20-3191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723653/
https://www.ncbi.nlm.nih.gov/pubmed/33313091
http://dx.doi.org/10.21037/atm-20-3191

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