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Stromal cells promote chemoresistance of acute myeloid leukemia cells via activation of the IL-6/STAT3/OXPHOS axis
BACKGROUND: Bone marrow stromal cells (BMSCs) are known to promote chemoresistance in acute myeloid leukemia (AML) cells. However, the molecular basis for BMSC-associated AML chemoresistance remains largely unexplored. METHODS: The mitochondrial oxidative phosphorylation (OXPHOS) levels of AML cells...
Autores principales: | Hou, Diyu, Wang, Bin, You, Ruolan, Wang, Xiaoting, Liu, Jingru, Zhan, Weiwu, Chen, Ping, Qin, Tiandi, Zhang, Xuehao, Huang, Huifang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723653/ https://www.ncbi.nlm.nih.gov/pubmed/33313091 http://dx.doi.org/10.21037/atm-20-3191 |
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