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Alteration of fecal tryptophan metabolism correlates with shifted microbiota and may be involved in pathogenesis of colorectal cancer

BACKGROUND: Gut tryptophan (Trp) metabolites are produced by microbiota and/or host metabolism. Some of them have been proven to promote or inhibit colorectal cancer (CRC) in vitro and animal models. We hypothesized that there is an alteration of gut Trp metabolism mediated by microbiota and that it...

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Detalles Bibliográficos
Autores principales: Sun, Xi-Zhen, Zhao, Dong-Yan, Zhou, Yuan-Chen, Wang, Qian-Qian, Qin, Geng, Yao, Shu-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723673/
https://www.ncbi.nlm.nih.gov/pubmed/33362375
http://dx.doi.org/10.3748/wjg.v26.i45.7173