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Nimbolide inhibits tumor growth by restoring hepatic tight junction protein expression and reduced inflammation in an experimental hepatocarcinogenesis

BACKGROUND: Altered tight junction (TJ) proteins are correlated with carcinogenesis and tumor development. Nimbolide is a tetranotriterpenoid that has been shown to have antioxidant and anti-proliferative properties; however, its anticancer effects and molecular mechanism in hepatocellular carcinoma...

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Detalles Bibliográficos
Autores principales: Ram, Amit Kumar, Vairappan, Balasubramaniyan, Srinivas, BH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723674/
https://www.ncbi.nlm.nih.gov/pubmed/33362373
http://dx.doi.org/10.3748/wjg.v26.i45.7131