Hemophagocytic lymphohistiocytosis caused by STAT1 gain-of-function mutation is not driven by interferon-γ: A case report

BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyper-inflammatory syndrome caused by many genetic defects. STAT1 is a DNA-binding factor that regulates gene transcription. HLH caused by STAT1 gain-of-function (GOF) mutations has rarely been reported and its clinical manif...

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Detalles Bibliográficos
Autores principales: Liu, Nan, Zhao, Fen-Ying, Xu, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723692/
https://www.ncbi.nlm.nih.gov/pubmed/33344614
http://dx.doi.org/10.12998/wjcc.v8.i23.6130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723692/
https://www.ncbi.nlm.nih.gov/pubmed/33344614
http://dx.doi.org/10.12998/wjcc.v8.i23.6130

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