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Longitudinal characterization of HIV-1 pol-gene in treatment-naïve men-who-have-sex-with-men from acute to chronic infection stages

HIV-1 is characterized by its ability to mutate and recombine even at polymerase (pol) gene. However, pol-gene diversity is limited due to functional constraints. The aim of this study was to characterize longitudinally, by next-generation sequencing (NGS), HIV-1 variants based on pol-gene sequences...

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Detalles Bibliográficos
Autores principales: Cevallos, Cintia, Culasso, Andrés C.A., Modenutti, Carlos, Gun, Ana, Sued, Omar, Avila, María M., Flichman, Diego, Delpino, M. Victoria, Quarleri, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723807/
https://www.ncbi.nlm.nih.gov/pubmed/33319116
http://dx.doi.org/10.1016/j.heliyon.2020.e05679