LncRNA kcnq1ot1 promotes lipid accumulation and accelerates atherosclerosis via functioning as a ceRNA through the miR-452-3p/HDAC3/ABCA1 axis

Kcnq1 overlapping transcript 1 (kcnq1ot1), an imprinted antisense lncRNA in the kcnq1 locus, acts as a potential contributor to cardiovascular disease, but its role in atherosclerosis remains unknown. The aim of this study was to explore the effects of kcnq1ot1 on atherogenesis and the underlying me...

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Detalles Bibliográficos
Autores principales: Yu, Xiao-Hua, Deng, Wen-Yi, Chen, Jiao-Jiao, Xu, Xiao-Dan, Liu, Xian-Xia, Chen, Lei, Shi, Meng-Wen, Liu, Qi-Xian, Tao, Min, Ren, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723992/
https://www.ncbi.nlm.nih.gov/pubmed/33293505
http://dx.doi.org/10.1038/s41419-020-03263-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723992/
https://www.ncbi.nlm.nih.gov/pubmed/33293505
http://dx.doi.org/10.1038/s41419-020-03263-6

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