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Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission

Efficient neurotransmitter release at the presynaptic terminal requires docking of synaptic vesicles to the active zone membrane and formation of fusion-competent synaptic vesicles near voltage-gated Ca(2+) channels. Rab3-interacting molecule (RIM) is a critical active zone organizer, as it recruits...

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Détails bibliographiques
Auteurs principaux: Zarebidaki, Fereshteh, Camacho, Marcial, Brockmann, Marisa M., Trimbuch, Thorsten, Herman, Melissa A., Rosenmund, Christian
Format: Online Article Texte
Langue:English
Publié: Society for Neuroscience 2020
Sujets:
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724145/
https://www.ncbi.nlm.nih.gov/pubmed/33139401
http://dx.doi.org/10.1523/JNEUROSCI.1922-20.2020