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Obeticholic acid is associated with improvements in AST-to-platelet ratio index and GLOBE score in patients with primary biliary cholangitis

BACKGROUND & AIMS: Biochemical markers, including GLOBE score and aspartate aminotransferase-to-platelet ratio index (APRI), are used to stratify risk in patients with primary biliary cholangitis (PBC). This study aimed to evaluate the effects of obeticholic acid (OCA) on categorical shifts in G...

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Detalles Bibliográficos
Autores principales: Harms, Maren H., Hirschfield, Gideon M., Floreani, Annarosa, Mayo, Marlyn J., Parés, Albert, Liberman, Alexander, Malecha, Elizabeth Smoot, Pencek, Richard, MacConell, Leigh, Hansen, Bettina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724188/
https://www.ncbi.nlm.nih.gov/pubmed/33319187
http://dx.doi.org/10.1016/j.jhepr.2020.100191