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Engineered Lysins With Customized Lytic Activities Against Enterococci and Staphylococci

The emergence of multidrug-resistant bacteria has made minor bacterial infections incurable with many existing antibiotics. Lysins are phage-encoded peptidoglycan hydrolases that have demonstrated therapeutic potential as a novel class of antimicrobials. The modular architecture of lysins enables th...

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Detalles Bibliográficos
Autores principales: Binte Muhammad Jai, Hana Sakina, Dam, Linh Chi, Tay, Lowella Servito, Koh, Jodi Jia Wei, Loo, Hooi Linn, Kline, Kimberly A., Goh, Boon Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724435/
https://www.ncbi.nlm.nih.gov/pubmed/33324362
http://dx.doi.org/10.3389/fmicb.2020.574739