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TET1 and 5-Hydroxymethylation Preserve the Stem Cell State of Mouse Trophoblast

The ten-eleven translocation factor TET1 and its conferred epigenetic modification 5-hydroxymethylcytosine (5hmC) have important roles in maintaining the pluripotent state of embryonic stem cells (ESCs). We previously showed that TET1 is also essential to maintain the stem cell state of trophoblast...

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Detalles Bibliográficos
Autores principales: Senner, Claire E., Chrysanthou, Stephanie, Burge, Sarah, Lin, Hai-Yan, Branco, Miguel R., Hemberger, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724466/
https://www.ncbi.nlm.nih.gov/pubmed/32442533
http://dx.doi.org/10.1016/j.stemcr.2020.04.009