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TET1 and 5-Hydroxymethylation Preserve the Stem Cell State of Mouse Trophoblast
The ten-eleven translocation factor TET1 and its conferred epigenetic modification 5-hydroxymethylcytosine (5hmC) have important roles in maintaining the pluripotent state of embryonic stem cells (ESCs). We previously showed that TET1 is also essential to maintain the stem cell state of trophoblast...
Autores principales: | Senner, Claire E., Chrysanthou, Stephanie, Burge, Sarah, Lin, Hai-Yan, Branco, Miguel R., Hemberger, Myriam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724466/ https://www.ncbi.nlm.nih.gov/pubmed/32442533 http://dx.doi.org/10.1016/j.stemcr.2020.04.009 |
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