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Rebooting the Epigenomes during Mammalian Early Embryogenesis

Upon fertilization, terminally differentiated gametes are transformed to a totipotent zygote, which gives rise to an embryo. How parental epigenetic memories are inherited and reprogrammed to accommodate parental-to-zygotic transition remains a fundamental question in developmental biology, epigenet...

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Detalles Bibliográficos
Autores principales: Xia, Weikun, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724468/
https://www.ncbi.nlm.nih.gov/pubmed/33035464
http://dx.doi.org/10.1016/j.stemcr.2020.09.005